Joi & Blokes is a hormone-and-wellness telehealth program, Joi for women and Blokes for men, that also prescribes compounded GLP-1 medication: semaglutide at $199 a month and tirzepatide at $299 a month, both billed quarterly, so the first charge is $497 or $747, not the monthly headline number. The program’s genuine strength is a named, independently verified medical director, Dr. Melissa Loseke, DO. Its GLP-1 track record is thinner than that credential suggests: an independent review notes that Joi & Blokes’ roots and most of its reviews sit in hormone replacement therapy, with GLP-1 one item on a larger wellness menu rather than the core business.
Below: what Joi and Blokes actually are as two brands sharing one program, the real quarterly cost with the first-payment shock priced out, Dr. Loseke’s credentials in full, what the BBB record and the pooled Trustpilot listings show, who should look elsewhere, and how Joi & Blokes’ computed score compares against TrimRx, ReadyRx, AltRx and Zevay on the same rubric.
Key takeaways
Is Joi & Blokes legit?
Yes. Joi & Blokes is a real prescription telehealth program with a named, independently verified medical director, Dr. Melissa Loseke, DO. Its Better Business Bureau profile, filed under Joi Women’s Wellness, shows a B rating with 6 complaints and no accreditation, a genuinely mixed but checkable record.
How much does Joi & Blokes cost?
Compounded semaglutide is $199 a month and compounded tirzepatide is $299 a month, but both are billed quarterly. The real first payment is $497 for semaglutide ($99 plus $199 plus $199) or $747 for tirzepatide ($149 plus $299 plus $299), not the monthly figure alone.
Who is Joi & Blokes’ medical director?
Dr. Melissa Loseke, DO, independently verified through Doximity’s physician listing and a November 2025 press release naming her as the leader of the Joi & Blokes clinical team. This is a real, sourced, named credential, not a marketing claim.
What is Joi & Blokes’ BBB rating?
B, with 6 complaints filed and no BBB accreditation, under the legal name Joi Women’s Wellness, based in Denver, Colorado, read directly from BBB’s own profile on 16 July 2026.
Scored against five criteria, 0 to 2 each. A criterion we could not verify scores zero rather than taking the company's word for it. We do not restate Joi & Blokes's Trustpilot score: it moves, so we link the profile instead and you read it live.
| Criterion | Score | Why |
|---|---|---|
| BBB accreditation | 1/2 | BBB rates Joi Women's Wellness B, with 6 complaints filed; the business is not BBB accredited. Source |
| Certification and pharmacy | 0/2 | Not verified as of 16 July 2026. |
| Price when the dose rises | 0/2 | Not verified as of 16 July 2026. |
| Price transparency | 1/2 | Joi & Blokes lists semaglutide at $199/mo and tirzepatide at $299/mo, billed quarterly with an itemized first payment ($497 and $747 respectively); this pricing is corroborated by one independent review, not by a second source. Source |
| Track record and coverage | 2/2 | Medical Director Dr. Melissa Loseke, DO is independently verified: Doximity lists her as a licensed physician (Des Moines University College of Osteopathic Medicine, class of 2006; family medicine residency at the University of Nebraska Medical Center, 2008 to 2011), and a BusinessWire release confirms she leads the Joi & Blokes clinical team. Source |
Two brands, one program
Joi and Blokes are two brand names inside one clinical program, not two separate companies, and that matters because their online reputations appear to be pooled rather than kept apart. Joi is registered with the Better Business Bureau under the legal name Joi Women’s Wellness, based in Denver, Colorado. On Trustpilot, a profile is indexed at trustpilot.com/review/blokes.co and shown in search results under two different labels, “Blokes – Modern Men’s Health” and “Joi and Blokes”, which suggests a merged or renamed listing rather than two cleanly separate ones. We could not open that page directly ourselves, a fetch attempt returned an HTTP 403 error, so this is search-result evidence, not a page we read first-hand.
Searching specifically for a Trustpilot profile under the domain joi.com turned up nothing: no profile exists there. The real combined profile instead appears to be filed under a third domain, joiandblokes.com, at trustpilot.com/review/joiandblokes.com. We are not going to state a score for either listing. A rating built by pooling two brands’ reviews together can flatter whichever brand has the weaker independent reputation on its own, and reprinting a pooled number as if it described the GLP-1 program specifically is exactly the kind of misleading shortcut this rewrite exists to remove. Read the profiles yourself and weigh what a merged rating actually tells you before you rely on it.
What Joi & Blokes costs
Joi & Blokes’ real cost is not the $199 or $299 monthly headline, it is the quarterly bill: both GLP-1 plans are billed three months at a time, and the first payment lands well above a single month’s rate. Compounded semaglutide runs $199 a month, but the quarterly structure means the first charge is $497, made up of a $99 first month plus two $199 months. Compounded tirzepatide runs $299 a month, with a first quarterly payment of $747, made up of a $149 first month plus two $299 months. Source for both figures: an independent review of Joi & Blokes (clearmetabolic.com).
| Medication | Monthly rate | First quarterly payment | Breakdown |
|---|---|---|---|
| Compounded semaglutide | $199/mo | $497 | $99 + $199 + $199 |
| Compounded tirzepatide | $299/mo | $747 | $149 + $299 + $299 |
Prices verified 16 July 2026; confirm your current price with Joi & Blokes before you pay. A quarterly-billed plan is a bigger up-front payment step than a monthly plan from a provider like TrimRx, and that is exactly the kind of detail worth confirming in writing before you commit three months at a time.
A named medical director
Joi & Blokes’ genuine strength on this page is a named, independently verified medical director: Dr. Melissa Loseke, DO. Doximity’s own physician listing confirms she trained at Des Moines University College of Osteopathic Medicine, class of 2006, and completed a Family Medicine residency at the University of Nebraska Medical Center from 2008 to 2011 (doximity.com). A November 2025 press release corroborates that she leads the Joi & Blokes clinical team, naming her specifically in connection with an 11-clinician consultation program the company launched for patients with existing lab work (businesswire.com).
Unlike the pricing and reputation questions elsewhere on this page, this is not an open question. A named, licensed physician with a documented training history sits behind the clinical program, and that is a real, checkable credential, not a marketing claim we were unable to verify. It is the single strongest point in Joi & Blokes’ favor on this site’s rubric, and it is reflected directly in the score above.
What we could and could not verify
Joi & Blokes’ Better Business Bureau profile, filed under the legal name Joi Women’s Wellness in Denver, Colorado, shows a B letter rating and 6 complaints filed against the business, and the company is not BBB accredited (bbb.org), read directly on 16 July 2026. A B rating with a small number of complaints is a meaningfully different record from AltRx’s F rating and 37 unanswered complaints, and it is worth naming as a genuine point in Joi & Blokes’ favor rather than treating every provider’s BBB record as interchangeable.
No LegitScript badge appears anywhere on joiandblokes.com’s homepage, and no third-party source makes a LegitScript certification claim on Joi & Blokes’ behalf either, as of 16 July 2026. Record that precisely: this is a certification we found no evidence for, in either direction, not a certification we confirmed Joi & Blokes lacks. Several other providers scored on this site at least display a badge on their own site, even where that badge could not be independently confirmed; Joi & Blokes does not have even that.
The Trustpilot picture, covered in full above, is that reviews for Joi and reviews for Blokes appear to be pooled into shared or overlapping listings rather than kept separate by brand. That means a rating attached to one label may reflect experiences with the other brand’s clinicians, scheduling or billing, not the GLP-1 program specifically. We are not stating a score for either profile, only that the pooling itself is a real, sourced fact worth knowing before you read one.
Who Joi & Blokes is not for
Joi & Blokes is not the right choice for anyone who wants a GLP-1-first provider, one whose main business and bulk of independent reputation is built around weight-loss medication specifically. An independent review notes that Joi & Blokes’ roots and most of its reviews sit in hormone replacement therapy, and that GLP-1 is one item on a larger wellness menu rather than the platform’s core business (clearmetabolic.com). If semaglutide or tirzepatide is the only thing you want from a provider, a GLP-1-focused platform may fit that need more directly.
It is also not the right choice for anyone who cannot absorb a $497 or $747 first payment. The quarterly billing structure means the first charge is roughly two and a half times a single month’s rate, and none of the sources we checked document a month-to-month option for Joi & Blokes’ GLP-1 plans, unlike TrimRx’s flat monthly pricing.
Finally, it is not the right choice for anyone who wants a brand-specific Trustpilot rating to judge Joi or Blokes on its own. Because the two brands’ reviews appear to be pooled, a rating attached to either label may not describe the specific clinician, program or billing experience you would actually encounter.
How Joi & Blokes compares
Joi & Blokes scores 2.0 out of 5 on this site’s rubric, tied with ReadyRx for second place, carried mainly by its track record, where Dr. Loseke’s verified credentials weigh heavily, and held back by a lack of independently confirmed certification and dose-flat pricing. The table below applies the same five criteria and the same 0-to-2 scoring used throughout this site to all five providers, from the same evidence table, so the comparison is apples to apples.
| Provider | BBB accreditation | Certification | Price flat as dose rises | Price transparency | Track record | Score |
|---|---|---|---|---|---|---|
| TrimRx | 2/2 | 0/2 | 2/2 | 1/2 | 1/2 | 3.0/5 |
| Joi & Blokes | 1/2 | 0/2 | 0/2 | 1/2 | 2/2 | 2.0/5 |
| ReadyRx | 0/2 | 1/2 | 0/2 | 2/2 | 1/2 | 2.0/5 |
| AltRx | 0/2 | 1/2 | 0/2 | 0/2 | 0/2 | 0.5/5 |
| Zevay | 0/2 | 0/2 | 0/2 | 0/2 | 0/2 | 0.0/5 |
Joi & Blokes’ strongest point on this table is track record, where its named and independently verified medical director outweighs the thinner GLP-1-specific reputation described above. Its weakest points are certification, no LegitScript badge or third-party claim was found at all, and dose pricing, where no source we checked says whether Joi & Blokes’ price rises as a patient’s dose is titrated upward. TrimRx and Zevay are the only two providers in this comparison with dose-pricing evidence one way or the other; Joi & Blokes is simply unverified on that specific question, not confirmed to charge more at higher doses.
What you can be prescribed
Joi & Blokes prescribes compounded semaglutide and compounded tirzepatide, the same two GLP-1-class medications every provider scored on this site prescribes, inside a broader hormone-and-wellness program built around Dr. Melissa Loseke’s clinical team. The decision in front of you is not which medication you can access, it is whether a broader workup under a named medical director, and a quarterly billing structure with a large first payment, fits what you actually want from a GLP-1 provider.
These providers prescribe tirzepatide and semaglutide, which are FDA-approved. We may earn a commission, and it never changes your price.
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#1
TrimRxPersonalized programs, US pharmacies
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#2
Joi & BlokesHis & hers compounded GLP-1s
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#3
ReadyRxFast approvals on weight-loss meds
Visit site
If a named clinical lead and a wider wellness program are what you are looking for, and you can absorb the quarterly first payment, that is a reasonable reason to choose Joi & Blokes. If GLP-1 medication specifically, at the lowest possible friction, is all you want, the comparison table above gives you a same-criteria look at four providers built around that instead.
Joi & Blokes reviews: frequently asked questions
Is Joi & Blokes legit?
Yes. Joi & Blokes is a real prescription telehealth program with a named, independently verified medical director, Dr. Melissa Loseke, DO, confirmed through Doximity’s physician listing and a November 2025 press release. Its BBB profile, filed under Joi Women’s Wellness, shows a B rating with 6 complaints and no accreditation, a mixed but genuinely checkable record, not a red flag on its own.
How much does Joi & Blokes cost for GLP-1?
Compounded semaglutide is $199 a month and compounded tirzepatide is $299 a month, both billed quarterly. Prices verified 16 July 2026; confirm your current price with Joi & Blokes before you pay, since the quarterly structure means your actual first charge is $497 or $747, not the monthly figure alone.
Why is the first payment so much higher than the monthly price?
Because Joi & Blokes bills quarterly, not monthly. Semaglutide’s first payment is $497, made up of a $99 first month plus two $199 months; tirzepatide’s first payment is $747, made up of a $149 first month plus two $299 months, per an independent review of the program (clearmetabolic.com).
Who is Joi & Blokes’ medical director?
Dr. Melissa Loseke, DO. Doximity’s physician listing confirms she trained at Des Moines University College of Osteopathic Medicine, class of 2006, and completed a Family Medicine residency at the University of Nebraska Medical Center from 2008 to 2011. A November 2025 press release separately confirms she leads the Joi & Blokes clinical team.
What is Joi & Blokes’ BBB rating?
B, with 6 complaints filed against the business, and no BBB accreditation, filed under the legal name Joi Women’s Wellness in Denver, Colorado, read directly from BBB’s own profile on 16 July 2026.
Is Joi & Blokes LegitScript certified?
No badge or claim found. As of 16 July 2026, no LegitScript badge appears on joiandblokes.com’s homepage, and no third-party source makes a certification claim on Joi & Blokes’ behalf either. That is a gap in what could be found, not a confirmed absence of certification.
Does Joi & Blokes have a Trustpilot rating?
A profile exists, but this page will not state its score. A Trustpilot listing is indexed at trustpilot.com/review/blokes.co under two labels, “Blokes – Modern Men’s Health” and “Joi and Blokes,” and a separate profile sits at trustpilot.com/review/joiandblokes.com. No profile exists under joi.com. Because reviews for both brands appear to be pooled, a single number would not describe the GLP-1 program specifically, so read the live listings yourself.
Is GLP-1 Joi & Blokes’ main focus?
No, not according to an independent review of the program, which notes that Joi & Blokes’ roots and most of its reviews are in hormone replacement therapy, with GLP-1 one item on a larger wellness menu rather than the core business (clearmetabolic.com). Its strength is the named medical team behind the whole program, not a GLP-1-specific track record.